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Step 1
Heat oven to 425° F. Grease a 9x13 casserole dish or spray it with cooking spray.
Step 2
Brown ground beef in a large skillet over medium-high heat (breaking it up as you go) until no longer pink; drain off fat. If you are using extra-lean ground beef (or turkey), you can put a bit of olive oil in the pan to keep it from sticking.
Step 3
Add ketchup, onion powder, garlic powder, ½ teaspoon pepper, and 2 cups of shredded cheese. Stir well to combine.
Step 4
Scoop mix into the prepared 9x13" baking dish and spread evenly. Top beef mixture with remaining one cup of cheese.
Step 5
Separate biscuits in half, dividing top and bottom to make them thinner. Using whole biscuits instead of halves can make it so the bottom doesn’t cook and the top over cooks, so don't skip this step.
Step 6
Arrange biscuits on top of the casserole (should fit 12 biscuits).
Step 7
Bake for 10 to 15 minutes or until biscuits are golden brown and cooked through.
Step 8
Brush melted butter on top of the biscuits and serve.