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Preheat oven to 350 degrees F. Prepare a 2-part broiler pan by lining the bottom one with foil and spraying the top one with cooking spray.
In a very large bowl, tear the bread into 1/2 inch pieces. Pour the milk over it and add the eggs. Beat until a wet smooth mixture forms. Add the beef, cheese, and seasonings. Using your hands, squeeze and mix until everything is evenly distributed throughout.
Form into a loaf shape on the prepared broiler pan. Place strips of bacon crosswise and slightly overlapping on top of the loaf. Tuck ends underneath.
Stir ketchup, brown sugar, and seasonings together and spread evenly on top of the loaf. Bake for about 1 hour or until loaf tests 150 degrees F in the center using a quick-read baking thermometer.