Step 1

In a small mixing bowl, add the Italian seasoning, salt, garlic powder, onion powder, paprika, and black pepper.

Step 2

Stir the ingredients together until they are fully combined and the mixture looks even.

Step 3

Take the seasoning mix and sprinkle it over 2 pounds of ground beef. Use your hands to mix the seasoning into the beef until the spices are evenly distributed throughout the meat.

Step 4

Transfer the seasoned ground beef into a loaf pan that has been lightly greased to prevent sticking.

Step 5

Preheat your oven to 350°F (180°C). Place the loaf pan in the oven and bake for 45 minutes, or until the meatloaf's internal temperature reaches 160°F (71°C). Use a meat thermometer to check the temperature.