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Export 11 ingredients for grocery delivery
Step 1
Preheat oven to 400°F and spray a large 11 x 8-inch baking dish with non-stick cooking spray.
Step 2
Add the chicken breasts to your baking dish and drizzle with olive oil. Sprinkle both sides with salt, pepper, and garlic powder, to season.
Step 3
Prepare your homemade buffalo sauce. In a small mixing bowl whisk together the Frank's Red Hot Sauce, melted butter, honey, lime juice, minced garlic, and onion powder. Season with additional salt, pepper, or honey, to taste.
Step 4
Pour your prepared buffalo sauce over the top of the chicken breasts. Thoroughly coat each chicken breast in sauce (I like to use kitchen tongs to rotate each chicken breast 1-2 times).
Step 5
Tent your baking dish with foil and transfer it to the oven. Bake, covered, for 20 minutes. Then uncover and continue to bake for an additional 5-15 minutes, or until internal temperature registers 160°F as measured with a digital meat thermometer.
Step 6
Remove from the oven and allow your chicken to rest for 5 minutes before serving.