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Mix the flour with the garlic powder, 1/2 tsp salt, and pepper in a flat dish. Lay each piece chicken in the flour mixture to coat all sides. If there is any remaining flour mixture, sprinkle it over the chicken.
In a large skillet, heat the olive oil and butter over medium to medium high heat. Once the butter is bubbly and hot, add the chicken breast to the skillet in a single layer. Cook 3-4 minutes on the first side and then flip and cook and additional 3-4 minutes.
Remove chicken from skillet, and add asparagus and garlic, cooking 1 minute and stirring continually. Pour in the cooking wine and use the spoon to scrape the bottom of the pan as you stir to deglaze the pan. Continue to cook 2 minutes or until the liquid has reduced in half.
Stir in the heavy cream and remaining 1/2 tsp salt (or more to taste.) Bring to a boil, stirring regularly. Once the cream is boiling, add the chicken back into the sauce and continue to cook for 3-5 minutes or until the sauce has thickened.
Remove from heat. Sauce will continue to thicken as it cools. Serve over potatoes, wilted spinach, or rice. Enjoy!