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Step 1
Preheat the oven to 375F. Lightly spray a 13x9-inch casserole dish with cooking spray.
Step 2
In a large bowl, stir together the cream of chicken soup, sour cream, onion powder, garlic powder, salt, and pepper. Fold in the chicken and 1½ cups of cheese. Transfer the mixture to the prepared baking dish.
Step 3
In a medium bowl stir together the crackers and melted butter. Sprinkle crackers over the chicken mixture. Sprinkle with the remaining ½ cup of cheese.
Step 4
Bake for 35 to 40 minutes or until the filling is bubbling and the crackers are lightly browned. Allow the casserole to cool and set for 15 to 20 minutes before serving.