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Preheat oven to 350 degrees F.
In a large bowl combine meat, tomato juice, crackers, egg, onion, salt, pepper, garlic powder, oregano and cheese.
Mix to combine well.
Press into a loaf pan, or two mini loaf pans.
Bake for 1 hour, remove from the oven and let rest for 5-10 minutes. Drain off any fat and then slice to serve.