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Step 1
Preheat oven to 350 degrees F (175 degrees C).
Step 2
Mix Parmesan cheese, mayonnaise, and garlic powder together in a bowl.
Step 3
Arrange chicken breasts in a 9x13-inch baking dish; top with artichoke hearts and crimini mushrooms. Spread cheese mixture over the artichoke and mushroom layer.
Step 4
Bake in the preheated oven until the chicken no longer pink in the center and the juices run clear, about 30 minutes. An instant-read thermometer inserted into the center should read at least 165 degrees F (74 degrees C).