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Export 15 ingredients for grocery delivery
Step 1
Preheat the oven to 325 F.
Step 2
Season the brisket on both sides with ½ teaspoon kosher salt and ¼ teaspoon black pepper.
Step 3
In a large Dutch oven, heat the oil over medium-high heat.
Step 4
Add the brisket to the pot and sear until golden brown; flip and repeat.
Step 5
Remove from heat and add the onions.
Step 6
In a glass measuring cup or bowl, whisk to combine the ketchup, stock, garlic, brown sugar, paprika, white vinegar, and the remaining 1 teaspoon salt and ¼ teaspoon black pepper.
Step 7
Pour the sauce over the brisket to coat.
Step 8
Cover and bake for 2 ½–3 hours, or until the brisket is tender. Set aside.
Step 9
Bring a large pot of salted water to a boil over high heat.
Step 10
Add the pasta and cook until almost al dente.
Step 11
Drain and rinse with cold water to stop the cooking process. Set aside.
Step 12
In a large pot, melt the butter.
Step 13
Transfer 2 tablespoons of the melted butter into a bowl and toss with the panko to coat. Set aside.
Step 14
Add the flour to the remaining butter in the pot. Cook, whisking, until the color deepens, 1–2 minutes.
Step 15
Slowly add the milk, whisking until smooth with each addition until all of the milk has been added.
Step 16
Continue to cook over medium heat, whisking, until the mixture is slightly thickened and coats the back of a spoon.
Step 17
Remove from heat. Add the cheeses, salt, and pepper, and whisk until smooth.
Step 18
Add the drained pasta to the pot and stir to coat with the cheese sauce.
Step 19
Preheat the oven to 425 F.
Step 20
Lightly grease a 5-quart baking dish.
Step 21
Pour the pasta mixture evenly into the dish.
Step 22
Top with the panko mixture.
Step 23
Bake for 20–25 minutes, until golden brown.
Step 24
While the mac and cheese is baking, transfer the brisket to a cutting board, reserving the sauce in a bowl.
Step 25
Thinly slice the brisket, and then chop it into bite-sized pieces.
Step 26
Stir the brisket back into the sauce.
Step 27
Pour the brisket over the baked mac and cheese, then garnish with chopped parsley.
Step 28
Serve immediately.
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